Our faculty

Helen Blackwell

Professor, Department of Chemistry


The Blackwell lab studies chemical communication between bacteria and develops chemical strategies to intercept these pathways

Andrew Buller

Assistant Professor, Department of Chemistry


We are engineering enzymes to catalyze new reactions in vivo and studying their properties with kinetics, spectroscopy and X-ray crystallography.

Judith Burstyn

Professor, Department of Chemistry


We study heme-mediated allosteric regulation in small molecule-sensing proteins using bioinorganic and biophysical techniques.

Silvia Cavagnero

Professor, Department of Chemistry


We explore the fundamental principles of protein folding and aggregation in the cell, focusing on the role of the ribosome, molecular chaperones and nascent-protein dynamics.

Josh Coon

Professor, Department of Chemistry


We develop and apply mass spectrometric technology to study human health.

John Denu

Professor, Department of Biomolecular Chemistry


The Denu lab is currently focused on understanding the molecular links between metabolism and epigenetic pathways in human health and age-associated diseases.

Katrina Forest

Professor of Bacteriology and Biophysics


We study structures, functions, and mechanisms of bacterial proteins important for physiology and symbiosis using crystallography, microbiology, and (bio)chemical tools.

Ying Ge

Associate Professor, Department of Chemistry


We develop ultra high-resolution mass spectrometry-based top-down proteomics and metabolomics technologies for cardiac systems biology and precision medicine.

Samuel Gellman

Professor, Department of Chemistry


We study the structures and functions of proteins and protein-inspired molecules.  Biology gives us the former; the latter we invent.

Katherine Henzler-Wildman

Associate Professor, Department of Biochemistry


We study the molecular mechanisms of transporters and ion channels using NMR spectroscopy, functional assays, and chemical and biophysical tools

Aaron Hoskins

Associate Professor, Department of Biochemistry


We are interested in understanding pre-mRNA splicing and post-transcriptional gene regulation using chemical, biological, and physical tools.

James Keck

Professor, Department of Biomolecular Chemistry


Research in the Keck lab examines the structural mechanisms that drive DNA replication, replication restart, recombination, and repair reactions.

David Lynn

Professor, Department of Chemistry


We design new types of smart and responsive soft materials, including polymers, surfactants, surfaces, and interfaces that interact with biological systems.

Jeffrey Martell

Assistant Professor, Department of Chemistry


My group aims to develop hybrid synthetic/biological catalysts that mimic natural enzymes while exhibiting superior stability and chemical reactivity.

Dave Pagliarini

Associate Professor, Department of Biochemistry


We integrate large-scale approaches with classical biochemistry/chemical biology to study the modulation and basic metabolic function of mitochondria.

Vatsan Raman

Assistant Professor, Department of Biochemistry


We design small molecule biosensors for synthetic biology by computational protein design, multiplexed cell-based screening and deep sequencing.

M. Thomas Record

Professor, Department of Biochemistry


We study RNA polymerase as a chemical and physical machine in transcription initiation, and study solute-solute interactions to interpret solute effects on protein processes.

Alessandro Senes

Associate Professor, Department of Biochemistry


We are interested in understanding the chemical forces that modulate the interactions of membrane proteins.

Lloyd Smith

Professor, Department of Chemistry


We develop powerful new mass spectrometic tools for the comprehensive elucidation of proteoforms and proteoform families in biological systems.

Weiping Tang

Professor, Department of Chemistry


We are interested in developing new chemical reactions for carbohydrate synthesis and novel chemical tools to induce protein ubiquitination and subsequent degradation.

Martin Zanni

Professor, Department of Chemistry


Cutting-edge laser spectroscopy, such as 2D-IR spectroscopy and imaging, to advance difficult problems in biophysics and structural biology.