Our faculty Helen Blackwell Professor, Department of Chemistry firstname.lastname@example.org The Blackwell lab studies chemical communication between bacteria and develops chemical strategies to intercept these pathways Andrew Buller Assistant Professor, Department of Chemistry email@example.com We are engineering enzymes to catalyze new reactions in vivo and studying their properties with kinetics, spectroscopy and X-ray crystallography. Judith Burstyn Professor, Department of Chemistry firstname.lastname@example.org We study heme-mediated allosteric regulation in small molecule-sensing proteins using bioinorganic and biophysical techniques. Silvia Cavagnero Professor, Department of Chemistry email@example.com We explore the fundamental principles of protein folding and aggregation in the cell, focusing on the role of the ribosome, molecular chaperones and nascent-protein dynamics. Josh Coon Professor, Department of Chemistry firstname.lastname@example.org We develop and apply mass spectrometric technology to study human health. John Denu Professor, Department of Biomolecular Chemistry email@example.com The Denu lab is currently focused on understanding the molecular links between metabolism and epigenetic pathways in human health and age-associated diseases. Katrina Forest Professor of Bacteriology and Biophysics firstname.lastname@example.org We study structures, functions, and mechanisms of bacterial proteins important for physiology and symbiosis using crystallography, microbiology, and (bio)chemical tools. Ying Ge Associate Professor, Department of Chemistry email@example.com We develop ultra high-resolution mass spectrometry-based top-down proteomics and metabolomics technologies for cardiac systems biology and precision medicine. Samuel Gellman Professor, Department of Chemistry firstname.lastname@example.org We study the structures and functions of proteins and protein-inspired molecules. Biology gives us the former; the latter we invent. Katherine Henzler-Wildman Associate Professor, Department of Biochemistry email@example.com We study the molecular mechanisms of transporters and ion channels using NMR spectroscopy, functional assays, and chemical and biophysical tools Aaron Hoskins Associate Professor, Department of Biochemistry firstname.lastname@example.org We are interested in understanding pre-mRNA splicing and post-transcriptional gene regulation using chemical, biological, and physical tools. James Keck Professor, Department of Biomolecular Chemistry email@example.com Research in the Keck lab examines the structural mechanisms that drive DNA replication, replication restart, recombination, and repair reactions. David Lynn Professor, Department of Chemistry firstname.lastname@example.org We design new types of smart and responsive soft materials, including polymers, surfactants, surfaces, and interfaces that interact with biological systems. Jeffrey Martell Assistant Professor, Department of Chemistry email@example.com My group aims to develop hybrid synthetic/biological catalysts that mimic natural enzymes while exhibiting superior stability and chemical reactivity. Dave Pagliarini Associate Professor, Department of Biochemistry DPagliarini@morgridge.org We integrate large-scale approaches with classical biochemistry/chemical biology to study the modulation and basic metabolic function of mitochondria. Vatsan Raman Assistant Professor, Department of Biochemistry firstname.lastname@example.org We design small molecule biosensors for synthetic biology by computational protein design, multiplexed cell-based screening and deep sequencing. M. Thomas Record Professor, Department of Biochemistry email@example.com We study RNA polymerase as a chemical and physical machine in transcription initiation, and study solute-solute interactions to interpret solute effects on protein processes. Alessandro Senes Associate Professor, Department of Biochemistry firstname.lastname@example.org We are interested in understanding the chemical forces that modulate the interactions of membrane proteins. Lloyd Smith Professor, Department of Chemistry email@example.com We develop powerful new mass spectrometic tools for the comprehensive elucidation of proteoforms and proteoform families in biological systems. Weiping Tang Professor, Department of Chemistry firstname.lastname@example.org We are interested in developing new chemical reactions for carbohydrate synthesis and novel chemical tools to induce protein ubiquitination and subsequent degradation. Martin Zanni Professor, Department of Chemistry email@example.com Cutting-edge laser spectroscopy, such as 2D-IR spectroscopy and imaging, to advance difficult problems in biophysics and structural biology.