Helen Blackwell
Credentials: Professor, Department of Chemistry
Email: blackwell@chem.wisc.edu
The Blackwell lab studies chemical communication between bacteria and develops chemical strategies to intercept these pathways
Andrew Buller
Credentials: Assistant Professor, Department of Chemistry
Email: arbuller@wisc.edu
We are engineering enzymes to catalyze new reactions in vivo and studying their properties with kinetics, spectroscopy and X-ray crystallography.
Judith Burstyn
Credentials: Professor, Department of Chemistry
Email: burstyn@chem.wisc.edu
We study heme-mediated allosteric regulation in small molecule-sensing proteins using bioinorganic and biophysical techniques.
Silvia Cavagnero
Credentials: Professor, Department of Chemistry
Email: cavagnero@chem.wisc.edu
We explore the fundamental principles of protein folding and aggregation in the cell, focusing on the role of the ribosome, molecular chaperones and nascent-protein dynamics.
Josh Coon
Credentials: Professor, Department of Chemistry
Email: jcoon@chem.wisc.edu
We develop and apply mass spectrometric technology to study human health.
John Denu
Credentials: Professor, Department of Biomolecular Chemistry
Email: john.denu@wisc.edu
The Denu lab is currently focused on understanding the molecular links between metabolism and epigenetic pathways in human health and age-associated diseases.
Katrina Forest
Credentials: Professor, Bacteriology and Biophysics
Email: forest@bact.wisc.edu
We study structures, functions, and mechanisms of bacterial proteins important for physiology and symbiosis using crystallography, microbiology, and (bio)chemical tools.
Ying Ge
Credentials: Associate Professor, Department of Chemistry
Email: ying.ge@wisc.edu
We develop ultra high-resolution mass spectrometry-based top-down proteomics and metabolomics technologies for cardiac systems biology and precision medicine.
Samuel Gellman
Credentials: Professor, Department of Chemistry
Email: gellman@chem.wisc.edu
We study the structures and functions of proteins and protein-inspired molecules. Biology gives us the former; the latter we invent.
Katherine Henzler-Wildman
Credentials: Associate Professor, Department of Biochemistry
Email: henzlerwildm@wisc.edu
We study the molecular mechanisms of transporters and ion channels using NMR spectroscopy, functional assays, and chemical and biophysical tools
Aaron Hoskins
Credentials: Associate Professor, Department of Biochemistry
Email: ahoskins@wisc.edu
We are interested in understanding pre-mRNA splicing and post-transcriptional gene regulation using chemical, biological, and physical tools.
James Keck
Credentials: Professor, Department of Biomolecular Chemistry
Email: jlkeck@wisc.edu
Research in the Keck lab examines the structural mechanisms that drive DNA replication, replication restart, recombination, and repair reactions.
Lingjun Li
Credentials: Professor, Department of Chemistry and School of Pharmacy
Email: lingjun.li@wisc.edu
The Li Lab is developing innovative mass spectrometric tools to advance neuroscience and pharmaceutical research and enable biomarker discovery via multi-omics approache
David Lynn
Credentials: Professor, Department of Chemistry
Email: david.lynn@wisc.edu
We design new types of smart and responsive soft materials, including polymers, surfactants, surfaces, and interfaces that interact with biological systems.
Jeffrey Martell
Credentials: Assistant Professor, Department of Chemistry
Email: jdmartell@wisc.edu
My group aims to develop hybrid synthetic/biological catalysts that mimic natural enzymes while exhibiting superior stability and chemical reactivity.
Dave Pagliarini
Credentials: Associate Professor, Department of Biochemistry
Email: DPagliarini@morgridge.org
We integrate large-scale approaches with classical biochemistry/chemical biology to study the modulation and basic metabolic function of mitochondria.
Vatsan Raman
Credentials: Assistant Professor, Department of Biochemistry
Email: sraman4@wisc.edu
We design small molecule biosensors for synthetic biology by computational protein design, multiplexed cell-based screening and deep sequencing.
M. Thomas Record
Credentials: Professor, Department of Biochemistry
Email: mtrecord@wisc.edu
We study RNA polymerase as a chemical and physical machine in transcription initiation, and study solute-solute interactions to interpret solute effects on protein processes.
Alessandro Senes
Credentials: Associate Professor, Department of Biochemistry
Email: senes@wisc.edu
We are interested in understanding the chemical forces that modulate the interactions of membrane proteins.
Lloyd Smith
Credentials: Professor, Department of Chemistry
Email: smith@chem.wisc.edu
We develop powerful new mass spectrometic tools for the comprehensive elucidation of proteoforms and proteoform families in biological systems.
Weiping Tang
Credentials: Professor, Department of Chemistry
Email: weiping.tang@wisc.edu
We are interested in developing new chemical reactions for carbohydrate synthesis and novel chemical tools to induce protein ubiquitination and subsequent degradation.
Tina Wang
Credentials: Assistant Professor, Department of Chemistry
Email: twang495@wisc.edu
We are interested in using directed evolution to address the problem of protein misfolding and developing biosensors for antibiotic discovery/characterization.
Amy Weeks
Credentials: Assistant Professor, Department of Biochemistry
Email: amweeks@wisc.edu
We engineer enzymatic tools to enable spatially- and temporally-resolved mapping of cellular post-translational modifications using mass spectrometry.
Martin Zanni
Credentials: Professor, Department of Chemistry
Email: zanni@chem.wisc.edu
Cutting-edge laser spectroscopy, such as 2D-IR spectroscopy and imaging, to advance difficult problems in biophysics and structural biology.